Eukaryotic Topoisomerases II

《英文msh詞典》Eukaryotic Topoisomerases II
[入口詞] Eukaryotic Topoisomerases II
[主題詞] DNA Topoisomerases,Type II,Eukaryotic
[英文釋義] Eukaryotic enzymes of the DNA TOPOISOMERASES,TYPE II class that catalyze ATP-dependent breakage of both strands of DNA,passage of the unbroken strands through the breaks,and rejoining of the broken strands. These enzymes bring about relaxation of the supercoiled DNA and resolution of a knotted circular DNA duplex. Isozymes of the eukaryotic DNA topoisomerase II consist of homodimers of alpha or beta subunits.

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